IVF has long been used for the treatment of infertility, although it is not an effective treatment in severe male infertility. Intra Cytoplasmic Sperm Injection (ICSI) is similar to IVF as eggs and sperm are collected from each partner or donor. ICSI differs in term to IVF as each egg is individually injected with a single sperm, bypassing the stage where the sperm has to naturally penetrate the egg. ICSI is used when the male partner has an abnormal semen analysis. ICSI procedure is very effective when there is a male infertility factor.
There are many fertility problems which ICSI helps to overcome. ICSI procedure is performed when the male partner produces too few sperms to perform artificial insemination (intrauterine insemination [IUI]) or IVF. Other conditions where ICSI may be used are: